SPEC Kit 346: Scholarly Output Assessment Activities  · 157
WASHINGTON UNIVERSITY IN ST. LOUIS
The Ocular Hypertension Treatment Study and Its Impact
https://becker.wustl.edu/about/news/impact-ocular-hypertension-treatment-study
The Ocular Hypertension Treatment Study and Its Impact | Becker Medical Library
https://becker.wustl.edu/about/news/impact-ocular-hypertension-treatment-study[4/24/15, 3:24:59 PM]
OHTS was the first study to identify central corneal thickness (CCT) as an independent risk factor for the
development of POAG. This finding was published in the 2002 article: The Ocular Hypertension Treatment
Study: Baseline factors that predict the onset of primary open-angle glaucoma. The term of “central
corneal thickness” was searched in PubMed to determine if there was an uptake in usage of the term.
While there is an increase in the term as noted in PubMed, the cause may be temporal and not directly
correlate to OHTS.
The 2007 review of the OHTS articles raised questions regarding the suitability of metrics based on
publication data to illustrate meaningful health outcomes or clinical applications. The project further
expanded to identify and locate evidence of research impact beyond use of publication metrics. Impact
includes meaningful health outcomes and other outcomes correlated with the diffusion of knowledge such
as new research studies, synthesis into clinical applications, or influence on public policy. Examples of
impact resulting from OHTS findings were identified and are illustrated in the Wordle image below.
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